2003-06-27

7 Oct 2013 Introduction: Ubiquitously expressed in the human body, glycoprotein 130 ( gp130) is a shared subunit of receptor complexes for at least nine 

Macrophage recruitment is essential for heart regeneration through the secretion of OSM, which promotes cardiomyocyte proliferation. As the coreceptor of OSM, gp130 activation is sufficient to promote cardiomyocyte proliferation by activating Yap through Src during heart regeneration. gp130 is … Gp130, a shared signal transducing receptor component for hematopoietic and neuropoietic cytokines J Neurochem. 1996 Jul;67(1):1-10. doi: 10.1046/j.1471-4159.1996.67010001.x.

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gp130 Antibody (E-8) is available as both the non-conjugated anti-gp130 antibody form, as well as multiple conjugated forms of anti-gp130 antibody, including View R&D Systems research products for gp130. 0.1 - 8 ng/mL (Cell Culture Supernates), 0.3 - 16 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) Gp130. Gene. gp130. Organism. Homo sapiens (Human) Status.

CAS Article Diverse cytokines can signal through receptor complexes containing the gp130 subunit.

Here, we investigate the cellular localization, regulation, and possible function of two IL-6 receptors (IL-6Ralpha and gp130) in mouse and human fallopian 

The binding of a ligand to its receptor induces the dimerization of GP130, leading to activation of the Jak tyrosine kinase and to tyrosine phosphorylation of GP130. View protein in InterPro IPR003961, FN3_dom IPR036116, FN3_sf IPR003529, Hematopoietin_rcpt_Gp130_CS IPR013783, Ig-like_fold IPR010457, IgC2-like_lig-bd IPR015321, TypeI_recpt_CBD: Pfam i: View protein in Pfam PF00041, fn3, 2 hits PF09240, IL6Ra-bind, 1 hit PF06328, Lep_receptor_Ig, 1 hit: SMART i: View Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130.

The Human CD130 (IL-6R-beta, gp130) ELISA is to be used for the in-vitro quantitative determination of soluble CD130 protein (gp130) in human serum, plasma 

Gp130

Syftet med denna studie var att mäta nivån av Oncostatin M (OSM) en gp130-cytokin i tandkörtelvätskan (GCF) och serum hos kroniska  Pedistalbågsmontage Navpod instrumentpod GP130 för infälld montering av GPS, ekolod, radar och multifunktionsskärmar. Navpod instrumentpod GP130 är  Munters installed GP130 air heaters, equipped with oil burners were installed to keep the greenhouse temperature under control during the cold season to avoid  GABRIEL Dammskyddsats, stötdämpare.

Gp130

2021-03-26 · The E3 ubiquitin ligase NEDD4L negatively regulates keratinocyte hyperplasia by inhibiting IL‐6/GP130/STAT3 signaling. NEDD4L directly interacts with GP130 and mediates its Lys‐27‐linked ubiquitination and proteasomal degradation. NEDD4L is reduced in the epidermis of psoriasis patients and negatively correlates with GP130 and p‐STAT3 Gp130 −/− embryos, which are generated by heterozygous crossing, also die between day 13 and term due to abnormal cardiac development . Therefore, although LIF binds LIFR and recruits GP130, the definitive role of LIFR and GP130 in implantation remains uncertain. gp130 antibodies were obtained from Cell Signaling Technology (Frankfurt am Main, Germany). 2.2 Cell proliferation assay L3.6plandAsPC-1cellswereseededin96-well plates(5,000 cells/well) and allowed to grow overnight.
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GP130 is a signal-transducing subunit shared by the receptors for the IL-6 family of cytokines (1-3). The binding of a ligand to its receptor induces the dimerization of GP130, leading to activation of the Jak tyrosine kinase and to tyrosine phosphorylation of GP130. View protein in InterPro IPR003961, FN3_dom IPR036116, FN3_sf IPR003529, Hematopoietin_rcpt_Gp130_CS IPR013783, Ig-like_fold IPR010457, IgC2-like_lig-bd IPR015321, TypeI_recpt_CBD: Pfam i: View protein in Pfam PF00041, fn3, 2 hits PF09240, IL6Ra-bind, 1 hit PF06328, Lep_receptor_Ig, 1 hit: SMART i: View Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family.

Author T Taga 1 Affiliation 1 Institute for Molecular 9 gp130 cytokines as agents of local control of PTH action. gp130 is a receptor subunit capable of intracellular signaling that is required for the cellular action of the IL-6 family of cytokines. The most well-known are interleukin IL-6 and IL-11, LIF, CT-1, OSM, and ciliary neurotrophic factor.
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[osen=로스앤젤레스 이상학 기자] "팀이 이겼으면 그보다 더 좋은 건 없다". la 다저스 류현진(26)이 호투에도 7승에 실패했다. 하지만 다저스의 시즌 첫

(D1) followed by a CBM (D2.